Stochastic Spatial Dynamics Enable Robust Cell Polarization

ثبت نشده
چکیده

3 Parameter Estimation 7 3.1 Model of FRAP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3.2 FRAP simulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3.3 FRAP experiments and Latrunculin A . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3.4 Boff and Soff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.5 Bon and Son . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 3.6 Aon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 3.7 Aoff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 3.8 Calculation of D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Spatial Stochastic Dynamics Enable Robust Cell Polarization

Although cell polarity is an essential feature of living cells, it is far from being well-understood. Using a combination of computational modeling and biological experiments we closely examine an important prototype of cell polarity: the pheromone-induced formation of the yeast polarisome. Focusing on the role of noise and spatial heterogeneity, we develop and investigate two mechanistic spati...

متن کامل

Robust inter and intra-cell layouts design model dealing with stochastic dynamic problems

In this paper, a novel quadratic assignment-based mathematical model is developed for concurrent design of robust inter and intra-cell layouts in dynamic stochastic environments of manufacturing systems. In the proposed model, in addition to considering time value of money, the product demands are presumed to be dependent normally distributed random variables with known expectation, variance, a...

متن کامل

Deterministic Versus Stochastic Cell Polarisation Through Wave-Pinning

Cell polarization is an important part of the response of eukaryotic cells to stimuli, and forms a primary step in cell motility, differentiation, and many cellular functions. Among the important biochemical players implicated in the onset of intracellular asymmetries that constitute the early phases of polarization are the Rho GTPases, such as Cdc42, Rac, and Rho, which present high active con...

متن کامل

Deterministic controlled-NOT gate for single-photon two-qubit quantum logic.

We demonstrate a robust implementation of a deterministic linear-optical controlled-not gate for single-photon two-qubit quantum logic. A polarization Sagnac interferometer with an embedded 45 degrees -oriented dove prism is used to enable the polarization control qubit to act on the momentum (spatial) target qubit of the same photon. The optical controlled-not gate requires no active stabiliza...

متن کامل

Mathematical analysis of spontaneous emergence of cell polarity.

Cell polarization, in which intracellular substances are asymmetrically distributed, enables cells to carry out specialized functions. While cell polarity is often induced by intracellular or extracellular spatial cues, spontaneous polarization (the so-called symmetry breaking) may also occur in the absence of spatial cues. Many computational models have been used to investigate the mechanisms ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013